Insulin Receptor alpha Chain

《英文msh詞典》Insulin Receptor alpha Chain
[入口詞] Insulin Receptor alpha Chain
[主題詞] Receptor,Insulin
[英文釋義] A cell surface receptor for INSULIN. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The receptor contains an intrinsic tyrosine kinase domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the LIVER; MUSCLE; and ADIPOSE TISSUE.